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Comparison of the therapeutic effects of lens capsular flap transplantation and autologous retinal transplantation in the management of refractory macular holes.
Wang, Qiaoyun; Xu, Yiqian; Guo, Yang; Zhang, Ji; Zhu, Manhui; Xie, Laiqing.
Afiliación
  • Wang Q; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Xu Y; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Guo Y; Lixiang Eye Hospital of Soochow University, Suzhou, China.
  • Zhang J; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Zhu M; Lixiang Eye Hospital of Soochow University, Suzhou, China. zhumanhuieye@126.com.
  • Xie L; Department of Ophthalmology, The Second Affiliated Hospital of Soochow University, Suzhou, China. xielaiqing@suda.edu.cn.
Int Ophthalmol ; 44(1): 324, 2024 Jul 09.
Article en En | MEDLINE | ID: mdl-38980539
ABSTRACT

PURPOSE:

To report the comparison of the therapeutic effects of lens capsular flap transplantation (LCT) and autologous retinal transplantation (ART) in refractory macular hole (MH) treatment.

METHODS:

Thirty-one patients (31 eyes) with refractory MH were retrospectively reviewed. The patients were divided into two groups based on the surgical procedures the LCT group (13 eyes) and the ART group (18 eyes). Patients were monitored for a minimum of 6 months. Best corrected visual acuity (BCVA), hole closure rate, postoperative central foveolar thickness (CFT), and some complications (e.g. graft loss or dislocation, postoperative retinal detachment, or postoperatively elevated intraocular pressure) were the primary outcome measures.

RESULTS:

The mean preoperative MH diameter was 1104 ± 287 µm in the LCT group and 1066 ± 297 µm in the ART group (t = 0.353, P = 0.727). The MH was closed in 12 patients (92.3%) of the LCT group and 17 patients (94.4%) of the ART group (χ2 = 0.057, P = 0.811); the MHs of 10 patients (76.9%) in the LCT group and 11 patients (61.1%) in the ART group were completely closed (χ2 = 0.864, P = 0.353). The BCVA improved from 2.3 ± 1.0 logMAR preoperatively to 1.3 ± 0.9 logMAR postoperatively in the LCT group and 2.3 ± 0.9 logMAR preoperatively to 1.0 ± 0.6 logMAR postoperatively in the ART group (postoperative BCVA vs preoperative BCVA in the LCT group t = 4.374, P = 0.001; postoperative BCVA vs preoperative BCVA in the ART group t = 5.899, P = 0.000018). The visual improvement was 1.3 ± 0.9 logMAR in the ART group and 1.0 ± 0.8 logMAR in the LCT group (t = - 1.033, P = 0.310). The postoperative CFT was 139.7 ± 48.3 µm in the LCT and 199.2 ± 25.1 µm in the ART group (t = - 4.062, P = 0.001). Graft dislocation emerged in 2 patients (15.4%) in the LCT group and 1 patient (5.6%) in the ART group.

CONCLUSIONS:

Applications of LCT and ART may both enhance anatomical and visual outcomes in refractory MH cases. The ART group exhibited a more optimal postoperative CFT than the LCT group one.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retina / Perforaciones de la Retina / Colgajos Quirúrgicos / Trasplante Autólogo / Vitrectomía / Agudeza Visual / Tomografía de Coherencia Óptica Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int Ophthalmol Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Retina / Perforaciones de la Retina / Colgajos Quirúrgicos / Trasplante Autólogo / Vitrectomía / Agudeza Visual / Tomografía de Coherencia Óptica Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int Ophthalmol Año: 2024 Tipo del documento: Article País de afiliación: China