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Association of Short-Term Increases in Ambient Fine Particulate Matter With Hospitalization for Asthma or COPD During Wildfire Season and Other Time Periods.
Horne, Benjamin D; Johnson, Mary M; Blagev, Denitza P; Haddad, Francois; Knowlton, Kirk U; Bride, Daniel; Bair, Tami L; Joy, Elizabeth A; Nadeau, Kari C.
Afiliación
  • Horne BD; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Johnson MM; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Blagev DP; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Haddad F; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Knowlton KU; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Bride D; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Bair TL; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Joy EA; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
  • Nadeau KC; Intermountain Medical Center Heart Institute (B. D. H., K. U. K., D. B., and T. L. B.), Salt Lake City, UT; the Division of Cardiovascular Medicine, Department of Medicine (B. D. H. and F. H.) and the Cardiovascular Institute (B. D. H. and F. H.), Stanford University, Stanford, CA; the Department of
CHEST Pulm ; 2(2)2024 Jun.
Article en En | MEDLINE | ID: mdl-38993972
ABSTRACT

BACKGROUND:

Short-term increases in air pollution are associated with poor asthma and COPD outcomes. Short-term elevations in fine particulate matter (PM2.5) due to wildfire smoke are becoming more common. RESEARCH QUESTION Are short-term increases in PM2.5 and ozone in wildfire season and in winter inversion season associated with a composite of emergency or inpatient hospitalization for asthma and COPD? STUDY DESIGN AND

METHODS:

Case-crossover analyses evaluated 63,976 and 18,514 patients hospitalized for primary discharge diagnoses of asthma and COPD, respectively, between January 1999 and March 2022. Patients resided on Utah's Wasatch Front where PM2.5 and ozone were measured by Environmental Protection Agency-based monitors. ORs were calculated using Poisson regression adjusted for weather variables.

RESULTS:

Asthma risk increased on the same day that PM2.5 increased during wildfire season (OR, 1.057 per + 10 µg/m3; 95% CI, 1.019-1.097; P = .003) and winter inversions (OR, 1.023 per +10 µg/m3; 95% CI, 1.010-1.037; P = .0004). Risk decreased after 1 week, but during wildfire season risk rebounded at a 4-week lag (OR, 1.098 per +10 µg/m3; 95% CI, 1.033-1.167). Asthma risk for adults during wildfire season was highest in the first 3 days after PM2.5 increases, but for children, the highest risk was delayed by 3 to 4 weeks. PM2.5 exposure was weakly associated with COPD hospitalization. Ozone exposure was not associated with elevated risks.

INTERPRETATION:

In a large urban population, short-term increases in PM2.5 during wildfire season were associated with asthma hospitalization, and the effect sizes were greater than for PM2.5 during inversion season.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: CHEST Pulm Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: CHEST Pulm Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos