Bacillus methanolicus: an emerging chassis for low-carbon biomanufacturing.

Yang, Xueting; Zheng, Zhaojuan; Wang, Yu

Yang, Xueting; Zheng, Zhaojuan; Wang, Yu.

Afiliación

Yang X; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
Zheng Z; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China. Electronic address: zhengzj@njfu.edu.cn.
Wang Y; Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; National Center of Technology Innovation for Synthetic Biology, Tianjin 300308, China. Electronic address: wang_y@tib.cas.cn.

Trends Biotechnol ; 2024 Jul 19.

Article en En | MEDLINE | ID: mdl-39033040

ABSTRACT

ABSTRACT

Bacillus methanolicus is a thermophilic methylotrophic bacterium that grows quickly on methanol in sea water-based media. It has been engineered for chemical bioproduction from methanol, but its efficiency needs improvement for industrialization. Synthetic biology approaches such as metabolic modeling and genome editing can reprogram B. methanolicus for low-carbon biomanufacturing.

Palabras clave

Bacillus methanolicus; genome editing; low-carbon biomanufacturing; methylotroph; synthetic biology; thermophile

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Trends Biotechnol / Trends biotechnol / Trends in biotechnology Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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