Comparison of bispectral index-guided endoscopic ultrasonography with continuous versus intermittent infusion of propofol: a retrospective study in Japan.
Clin Endosc
; 2024 Jul 24.
Article
en En
| MEDLINE
| ID: mdl-39044668
ABSTRACT
Background/Aims:
This study aimed to evaluate the safety and efficacy of continuous propofol infusion for anesthesia during endoscopic ultrasonography (EUS).Methods:
A total of 427 consecutive patients who underwent EUS between May 2018 and February 2019 were enrolled in this study. The patients were divided into two propofol infusion groups continuous (n=207) and intermittent (n=220). The following parameters were compared (1) propofol dose, (2) respiratory and circulatory depression, (3) body movement requiring discontinuation of the examination, (4) awakening score, and (5) patient satisfaction.Results:
The median total maintenance dose of propofol was significantly higher in the continuous group than in the intermittent group (160.0 mg vs. 130.0 mg, respectively); however, the reduction in SpO2 was significantly lower in the continuous group (2.9% vs. 13.2%). Body movements occurred less frequently in the continuous group than in the intermittent group (40.1% vs. 49.5%, respectively). The rate of complete awakening was significantly higher in the continuous group than in the intermittent group. Finally, there was a significant difference in the percentage of patients who answered "absolutely yes" when asked about receiving EUS again 52.7% in the continuous group vs. 34.3% in the intermittent group.Conclusions:
Continuous infusion resulted in stable sedation and reduced propofol-associated risks.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Clin Endosc
Año:
2024
Tipo del documento:
Article
País de afiliación:
Japón
Pais de publicación:
Corea del Sur