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The effect of RNLS gene polymorphisms on preeclampsia susceptibility: a meta-analysis study.
Salimi, Saeedeh; Mohammadpour-Gharehbagh, Abbas; Hedayat, Mohaddeseh; Galavi, Hamidreza; Harati-Sadegh, Mahdiyeh.
Afiliación
  • Salimi S; Department of Clinical Biochemistry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mohammadpour-Gharehbagh A; Cellular & Molecular Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Hedayat M; Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Galavi H; Department of Pharmacology & Toxicology, School of Pharmacy, Urmia University of Medical Sciences, Urmia, Iran.
  • Harati-Sadegh M; Department of Medicine, University of British Columbia, Vancouver, Canada.
Per Med ; 21(3): 191-204, 2024.
Article en En | MEDLINE | ID: mdl-39051664
ABSTRACT

Aim:

The authors designed a meta-analysis to find a comprehensive result of the impact of RNLS polymorphisms on preeclampsia (PE) susceptibility.

Methods:

The online databases PubMed, Scopus, and Google Scholar were employed for the purpose of literature search. Data analysis was conducted using STATA (ver. 12.0) and MetaGenyo web tool.

Results:

The findings showed that the RNLS rs10887800 polymorphism could increase risk of PE in allelic, codominant heterozygous and dominant genetic models. In addition, the analysis indicated that the RNLS rs2576178 polymorphism was associated with higher risk of PE in allelic, codominant homozygous, dominant, and recessive models.

Conclusion:

The findings of meta-analysis showed that the RNLS rs10887800 and rs2576178 polymorphisms could increase risk of PE in several genetic models.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple Límite: Female / Humans / Pregnancy Idioma: En Revista: Per Med Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Predisposición Genética a la Enfermedad / Polimorfismo de Nucleótido Simple Límite: Female / Humans / Pregnancy Idioma: En Revista: Per Med Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido