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Psychometric validation of the Chinese versions of EQ-5D-Y-3L and the experimental EQ-TIPS in children and adolescents with COVID-19.
Zhou, Wenjing; Li, Yaqin; Busschbach, Jan; Herdman, Michael; Yang, Zhihao; Lu, Yanming.
Afiliación
  • Zhou W; Department of Paediatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 2000, Jiangyue Road, Shanghai, China. zhoujing2188@163.com.
  • Li Y; Department of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands. zhoujing2188@163.com.
  • Busschbach J; Department of Paediatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, No. 2000, Jiangyue Road, Shanghai, China.
  • Herdman M; Department of Psychiatry, Section Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Yang Z; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
  • Lu Y; Health Services Management Department, Guizhou Medical University, Guiyang, China.
Eur J Health Econ ; 2024 Jul 27.
Article en En | MEDLINE | ID: mdl-39066840
ABSTRACT

OBJECTIVES:

Respiratory infectious diseases like COVID-19 profoundly impacts the health of children and adolescents, but validated instruments to measure their impacts on health-related quality of life (HRQoL) are lacking. The EQ-5D-Y-3L, widely used for youth HRQoL, now features a Chinese value set. The experimental EQ-TIPS addresses HRQoL assessment for toddlers and infants. This study tested the psychometric properties of both instruments in paediatric COVID-19 patients, and compared the performance of self-complete and proxy EQ-5D-Y-3L.

METHODS:

This longitudinal study recruited 861 COVID-19 patients aged 0-18 years and their parental caregivers, with 311 dyads completing the follow-up. Digital administration included the EQ-TIPS, the EQ-5D-Y-3L, and Overall Health Assessment (OHA). Controls comprised 231 healthy children. Analysis encompassed known-group validity, child-parent agreement, and responsiveness to change in disease severity and OHA.

RESULTS:

COVID-19 children exhibited lower HRQoL than non-infected peers. The EQ-TIPS and the EQ-5D-Y-3L distinguished groups by disease presence, severity and symptoms, showing moderate to good known-group validity (ESs 0.45-1.39 for EQ-TIPS, 0.44-1.91 for self-complete EQ-5D-Y-3L, and 0.32-1.67 for proxy EQ-5D-Y-3L). Child-parent agreement was moderate to good for EQ-5D-Y-3L (ICC 0.653-0.823; Gwet's AC1 0.470-0.738), and responsiveness was good for both EQ-TIPS Level Sum Score (LSS) (ESs 1.21-1.39) and EQ-5D-Y-3L index scores (ESs 1.00-1.16).

CONCLUSIONS:

This study demonstrates the reliability, validity, and responsiveness of the experimental EQ-TIPS and the EQ-5D-Y-3L in paediatric COVID-19 patients. It is the first evidence of the EQ-TIPS' responsiveness, supporting its use in assessing the impact of COVID-19 on paediatric HRQoL.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Health Econ Asunto de la revista: SAUDE PUBLICA / SERVICOS DE SAUDE Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Eur J Health Econ Asunto de la revista: SAUDE PUBLICA / SERVICOS DE SAUDE Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania