The Mediating Effect of Symptom Burden in the Depression and Quality of Life in Patients with Maintenance Hemodialysis.
Psychol Res Behav Manag
; 17: 2739-2746, 2024.
Article
en En
| MEDLINE
| ID: mdl-39070070
ABSTRACT
Objective:
To investigate current status of quality of life and the association between depression and symptom burden in a sample of Chinese maintenance hemodialysis (MHD) patients.Methods:
A self-designed patient general information questionnaire, disease-related information questionnaire, dialysis patient symptom burden scale, depression scale, and quality of survival scale were used to investigate 380 maintenance haemodialysis patients in haemodialysis centres. A regression model of the factors affecting the quality of survival was established using structural equation modelling.Results:
The regression model data had a high goodness of fit c2/df = 4.736, RMSEA = 0.099, GFI = 0.918, CFI = 0.972, TLI = 0.962, SRMR = 0.0469. Structural equation model analysis showed that depression had a positive predictive effect on symptom burden, ß = 0.398, P < 0.001; Symptom burden had a negative predictive effect on the quality of life, ß =-0.851, P < 0.001; and Depression had a negative predictive effect on the quality of life, ß =-0.151, P < 0.001. Depression indirectly affects the quality of life through symptom burdens.Conclusion:
Depression and symptom burden directly or indirectly affect the quality of life in patients with maintenance hemodialysis. Symptom burden moderates the relationship between depression and quality of life as a mediating variable.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Psychol Res Behav Manag
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Nueva Zelanda