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Advance of Near-Infrared Emissive Carbon Dots in Diagnosis and Therapy: Synthesis, Luminescence, and Application.
Hu, Jing; Zheng, Ziliang; Yang, Yongzhen; Chen, Lin; Kang, Weiwei.
Afiliación
  • Hu J; Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan, 030024, China.
  • Zheng Z; College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
  • Yang Y; Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital, Taiyuan, 030032, China.
  • Chen L; Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan, 030024, China.
  • Kang W; College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Adv Healthc Mater ; : e2401513, 2024 Aug 01.
Article en En | MEDLINE | ID: mdl-39091058
ABSTRACT
Carbon dots (CDs) with good optical properties, biocompatibility, easy functionalization, and small size have attracted more and more attention and laid a good foundation for their applications in the biomedicine field. CDs emitted in near-infrared regions (NIR-CDs) can achieve high penetration depth imaging and produce high cytotoxic substance for disease treatment. Therefore, NIR-CDs are promising materials to realize high-quality imaging-guided diagnostic and therapeutic integration. This review first introduces the current mainstream synthesis methods of NIR-CDs by "top-down" and "bottom-up". Second, the luminescence modes of NIR-CDs are introduced, and the luminescence mechanisms based on carbon core state, surface state, molecular state, and crosslinking enhanced emission are summarized. Third, the applications and principles of NIR-CDs in imaging, drug delivery, and non-invasive therapeutics are introduced from a view of diagnosis and therapy. Finally, their prospects and challenges in biomedical and biotechnological applications are outlined.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Adv Healthc Mater Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Adv Healthc Mater Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania