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Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases.
Dong, Wen-Sheng; Hu, Can; Hu, Min; Gao, Yi-Peng; Hu, Yu-Xin; Li, Kang; Ye, Yun-Jia; Zhang, Xin.
Afiliación
  • Dong WS; Department of Geriatrics, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan University at Jiefang Road 238, Wuhan, 430060, China.
  • Hu C; Department of Ultrasound, Union Hospital, Tongji Medical College, Clinical Research Center for Medical Imaging in Hubei Province, Hubei Province Key Laboratory of Molecular Imaging, Huazhong University of Science and Technology, Wuhan, Hubei, 430022, China.
  • Hu M; Department of Cardiology, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
  • Gao YP; Department of Cardiology, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
  • Hu YX; Department of Geriatrics, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan University at Jiefang Road 238, Wuhan, 430060, China.
  • Li K; Department of Geriatrics, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan University at Jiefang Road 238, Wuhan, 430060, China.
  • Ye YJ; Department of Geriatrics, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan University at Jiefang Road 238, Wuhan, 430060, China.
  • Zhang X; Department of Geriatrics, Hubei Key Laboratory of Metabolic and Chronic Diseases, Renmin Hospital of Wuhan University, Wuhan University at Jiefang Road 238, Wuhan, 430060, China. dr.zhangxin@whu.edu.cn.
Cell Commun Signal ; 22(1): 389, 2024 Aug 05.
Article en En | MEDLINE | ID: mdl-39103830
ABSTRACT
Modern human society is burdened with the pandemic of cardiovascular and metabolic diseases. Metrnl is a widely distributed secreted protein in the body, involved in regulating glucose and lipid metabolism and maintaining cardiovascular system homeostasis. In this review, we present the predictive and therapeutic roles of Metrnl in various cardiovascular and metabolic diseases, including atherosclerosis, ischemic heart disease, cardiac remodeling, heart failure, hypertension, chemotherapy-induced myocardial injury, diabetes mellitus, and obesity.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades Cardiovasculares / Enfermedades Metabólicas Límite: Animals / Humans Idioma: En Revista: Cell Commun Signal Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biomarcadores / Enfermedades Cardiovasculares / Enfermedades Metabólicas Límite: Animals / Humans Idioma: En Revista: Cell Commun Signal Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido