Deliberation concerning the role of M1-type macrophage subset in oral carcinogenesis.
J Exp Clin Cancer Res
; 43(1): 220, 2024 Aug 08.
Article
en En
| MEDLINE
| ID: mdl-39113068
ABSTRACT
Over the last decade, accumulating evidence has suggested that tumor-associated macrophages (TAMs) play a significant role in the tumor development. This commentary wishes to highlight the findings by You, et al. that M1-like TAMs could cascade a mesenchymal/stem-like phenotype of oral squamous cell carcinoma (OSCC) via the IL6/Stat3/THBS1 feedback loop. These unprecedented findings identified M1-like TAMs-regulated processes as potentially tumor-promotion in the context of OSCC immunomicroenvironment.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Boca
/
Macrófagos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Exp Clin Cancer Res
Año:
2024
Tipo del documento:
Article
País de afiliación:
China