Efficacy of sulodexide in treating idiopathic membranous nephropathy among Chinese patients: a meta-analysis.
Am J Transl Res
; 16(7): 2756-2764, 2024.
Article
en En
| MEDLINE
| ID: mdl-39114701
ABSTRACT
OBJECTIVE:
To evaluate the efficacy of Sulodexide in treating idiopathic membranous nephropathy (IMN) in the Chinese population.METHODS:
We systematically reviewed all eligible randomized clinical trials (RCTs) conducted in China that investigated the effects of Sulodexide on IMN. Three RCTs published between 2013 and 2022 were included, encompassing a total of 146 patients. The primary outcomes evaluated were changes in urine total protein (UTP), serum albumin (ALB), cholesterol (CHOL), and fibrinogen (FIB) levels.RESULTS:
Statistically significant differences were observed in the Sulodexide treatment group compared to the control group for the following parameters reduction in UTP and CHOL, increase in ALB, and reduction in FIB levels.CONCLUSION:
Sulodexide, when combined with conventional therapy, effectively reduces UTP and CHOL levels, decreases FIB levels, and increases ALB in Chinese patients with IMN.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Am J Transl Res
Año:
2024
Tipo del documento:
Article
País de afiliación:
China
Pais de publicación:
Estados Unidos