Diabetes mellitus and the risk of spontaneous bacterial peritonitis in patients with liver cirrhosis: a systematic review and meta-analysis.
Ann Saudi Med
; 44(4): 272-287, 2024.
Article
en En
| MEDLINE
| ID: mdl-39127903
ABSTRACT
BACKGROUND:
Spontaneous bacterial peritonitis (SBP) represents a critical and potentially lethal condition that typically develops in individuals with liver cirrhosis. This meta-analysis aimed to assess diabetes mellitus (DM) as a risk factor for SBP in liver cirrhotic patients.METHODS:
Following PRISMA guidelines, fifteen studies were included, for a total of 76 815 patients. The risk of bias was assessed using the Newcastle-Ottawa scale (NOS). We represented the results as risk ratios (RR) with the corresponding 95% confidence intervals (CI) using RevMan software. Additionally, we pooled the hazard ratios (HR) for developing SBP in patients with DM from the included studies.RESULTS:
The meta-analysis shows a significantly increased risk of SBP in cirrhotic patients with DM (HR 1.26; 95% CI [1.05-1.51], P=.01; HR 1.70; 95% CI [1.32-2.18], P<.001).CONCLUSIONS:
The study signifies that DM is an independent risk factor for SBP, emphasizing the need for targeted preventive measures in this specific population.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Peritonitis
/
Infecciones Bacterianas
/
Cirrosis Hepática
Límite:
Humans
Idioma:
En
Revista:
Ann Saudi Med
Asunto de la revista:
MEDICINA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Arabia Saudita
Pais de publicación: