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Use of Sodium-Glucose Cotransporter 2 Inhibitors in Hospitalized Patients.
Unlu, Ozan; Bhatt, Ankeet S; Blood, Alexander J.
Afiliación
  • Unlu O; Accelerator for Clinical Transformation, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Bhatt AS; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Blood AJ; Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.
JACC Adv ; 3(7): 101024, 2024 Jul.
Article en En | MEDLINE | ID: mdl-39129982
ABSTRACT
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have noted benefits in the treatment of type 2 diabetes, cardiovascular disease, heart failure, and chronic kidney disease. Despite these benefits, the adoption of SGLT2i in clinical practice has been slow. Early initiation of SGLT2i during hospitalization has been proposed to address this gap for 2 important reasons 1) it provides early clinical benefit in multiple disease states; and 2) hospitalization presents an opportunity for medication optimization and patient education, thereby overcoming clinical inertia. Challenges in SGLT2i adoption necessitate innovative strategies for integration into clinical practice. Ongoing trials and novel care delivery models are anticipated to further elucidate effective strategies for SGLT2i implementation and adherence. This review synthesizes the accrued evidence of SGLT2i across various chronic diseases. It emphasizes the rationale for early in-hospital initiation and discusses barriers and potential solutions for widespread implementation of SGLT2i in hospitalized patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Adv Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JACC Adv Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos