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Successful immunosuppressive drug-free immune tolerance induction in hemophilia B with inhibitor and anaphylaxis to factor IX: A case report.
Palomo Bravo, Ángeles; Prieto Bonilla, Rosario; Bardan Rebollar, Daniel; López-Jaime, Francisco José; Fernández-Bello, Ihosvany.
Afiliación
  • Palomo Bravo Á; Hematology Service Hospital Regional Universitario Materno-Infantil de Málaga Málaga Spain.
  • Prieto Bonilla R; Hematology Service Hospital Regional Universitario Materno-Infantil de Málaga Málaga Spain.
  • Bardan Rebollar D; Hematology Service Hospital Regional Universitario Materno-Infantil de Málaga Málaga Spain.
  • López-Jaime FJ; Thrombosis and Hemostasis Unit, Hematology Service Hospital Regional Universitario de Málaga Málaga Spain.
  • Fernández-Bello I; Thrombosis and Hemostasis Unit, Hematology Service Hospital Regional Universitario de Málaga Málaga Spain.
Clin Case Rep ; 12(8): e9312, 2024 Aug.
Article en En | MEDLINE | ID: mdl-39139619
ABSTRACT
Recommendations advise factor IX desensitization before immune tolerance induction in severe hemophilia B, supported by immunosuppression. A child with inhibitor and anaphylaxis to factor IX showed successful immunosuppression-free immune tolerance induction using very low and slowly increasing doses of a factor IX extended-half-life product. Immune tolerance to factor IX based on this protocol merits further study.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Case Rep Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido