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Biomedical properties, characterization of seaweeds species and antimicrobial activity.
Rizwan, S; Saleem, M; Hassan, H U; Raza, M A; Kanwal, R; Kabir, M; Ghaffar, R A; Fadladdin, Y A J; Rafiq, N; Matin, A; Khan, A; Gulahmadov, S Q; Arai, T.
Afiliación
  • Rizwan S; Jinnah University for Women, Department of Botany, Karachi, Pakistan.
  • Saleem M; Jinnah University for Women, Department of Botany, Karachi, Pakistan.
  • Hassan HU; University of Karachi, Department of Zoology, Karachi, Pakistan.
  • Raza MA; Ministry of National Food Security and Research, Fisheries Development Board, Islamabad, Pakistan.
  • Kanwal R; Government Postgraduate College Satellite Town, Department of Biology, Gujranwala, Pakistan.
  • Kabir M; University of Karachi, Department of Zoology, Karachi, Pakistan.
  • Ghaffar RA; Thal University Bhakkar, Department of Biological Sciences, Bhakkar, Punjab, Pakistan.
  • Fadladdin YAJ; University of Karachi, Department of Zoology, Karachi, Pakistan.
  • Rafiq N; King Abdulaziz University, Faculty of Sciences, Department of Biological Sciences, Jeddah, Kingdom of Saudi Arabia.
  • Matin A; Abdul Wali Khan University Mardan, Department of Zoology, Mardan, Pakistan.
  • Khan A; University of Baltistan Skarsu, Faculty of Natural and Health Sciences, Department of Biological Sciences, Skardu, Pakistan.
  • Gulahmadov SQ; University of Karachi, Department of Zoology, Karachi, Pakistan.
  • Arai T; Baku State University, Baku, Republic of Azerbaijan.
Braz J Biol ; 84: e280796, 2024.
Article en En | MEDLINE | ID: mdl-39140501
ABSTRACT
Marine organisms produce a variety of compounds with pharmacological activities. In order to better comprehend the medicinal value of five particular seaweed orders Ulvales (Ulva intestinalis), Bryopsidales (Codium decorticatum), Ectocarpales (Iyengaria stellata), Dictyotales (Spatoglossum aspermum) and Gigartinales (Hypnea musciformis), a bioactive analysis including the screening of phytochemical components, antioxidant and antimicrobial activities was the aim of the investigation. The species include U. intestinalis was collected from Sandspit, while C. decorticatum, I. stellata, S. aspermum, and H. musciformis were gathered from Buleji. These species evaluated for their ability to inhibit human infectious gram positive pathogens Staphylococcus aureus, Staphylococcus epidermidis as well as gram negative bacteria Escherichia coli. Additionally vegetable pathogen Fusarium oxysporum, and fruit pathogens (Aspergillus niger and Aspergillus flavus) were evaluated to determine the zone of inhibition. Two organic solvents, ethanol and methanol, were used to prepare seaweed extract. The disc diffusion method was utilized to quantify the zone of inhibition and the DPPH method was employed to measure the antioxidant activity. The study unveiled various phyto-constituents in the tested seaweeds, with flavonoids, tannins, and proteins found in all selected species, while saponins, terpenoids, and carbohydrates were absent in I. stellata and S. aspermum. Notably, ethanolic extracts of I. stellata and S. aspermum demonstrated superior higher antioxidant activity, with increasing percentages of inhibition from 1 to 6 mg/ml. Furthermore, the findings indicated that the ethanolic extract of U. intestinalis displayed the highest resistance against F. oxysporum and A. flavous among other seaweeds. Meanwhile, the ethanolic extract of C. decorticatum exhibited the highest resistance against A. Niger. Additionally, the ethanolic extract of I. stellata and H. musciformis displayed the highest resistance against the gram-negative bacteria E. coli and the gram-positive bacteria S. epidermidis, whereas the methanolic extract of U. intestinalis demonstrated the highest resistance against the gram-positive bacteria S. aureus. The findings of this investigation show that a range of bioactive compounds with antioxidant properties are involved in the antimicrobial activities of disease-causing pathogens.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algas Marinas / Antibacterianos Idioma: En Revista: Braz J Biol Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Brasil

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Algas Marinas / Antibacterianos Idioma: En Revista: Braz J Biol Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Pakistán Pais de publicación: Brasil