[A case of Parkinson's disease with marked head drop after administration of donepezil hydrochloride].
Rinsho Shinkeigaku
; 64(9): 664-667, 2024 Sep 26.
Article
en Ja
| MEDLINE
| ID: mdl-39183048
ABSTRACT
A 76-year-old woman with a 2-year history of Parkinson's disease presented with dropped head, which had developed rapidly after she had been prescribed donepezil hydrochloride (DNP) at 3â
|mg/day. After one month of medication, the extent of the head drop reached 90°. Examination revealed hypertrophy of the left sternocleidomastoid muscle, but no weakness of the extensor muscles in the cervical region. Surface electromyography demonstrated co-|contraction of the sternocleidomastoid and splenius capitus muscles during head flexion and extension. DNP was withdrawn, resulting in immediate amelioration of the head drop, and complete resolution was achieved after two months. Although head drop is often seen in patients with Parkinson's disease, few previous reports have documented DNP as a causative factor. If patients with Parkinson's disease develop head drop, it is important to investigate any history of DNP medication.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Piperidinas
/
Donepezilo
/
Indanos
Límite:
Aged
/
Female
/
Humans
Idioma:
Ja
Revista:
Rinsho Shinkeigaku
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Japón