Integrating sodium cholate-modified MOF hybrid lipase and solubilization of hydrophobic candidates into a step for liganding fishing lipase inhibitors from Nelumbinis Folium.

Hu, Wenxiang; Li, Jiayun; Zhang, Xindan; Lv, Yangbin; Ye, Hongwei; Li, Chenyue; Liu, Ehu; Chu, Chu

Hu, Wenxiang; Li, Jiayun; Zhang, Xindan; Lv, Yangbin; Ye, Hongwei; Li, Chenyue; Liu, Ehu; Chu, Chu.

Afiliación

Hu W; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
Li J; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, PR China.
Zhang X; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
Lv Y; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
Ye H; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
Li C; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China.
Liu E; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, PR China. Electronic address: liuehu2011@163.com.
Chu C; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, PR China. Electronic address: chuchu@zjut.edu.cn.

J Pharm Biomed Anal ; 251: 116430, 2024 Aug 27.

Article en En | MEDLINE | ID: mdl-39197203

Palabras clave

Lipase inhibitors; Molecular docking; Nelumbinis Folium; Sodium cholate; Zeolitic imidazolate framework-8

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Pharm Biomed Anal Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido

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