[A serological criterion for Bechterew's disease. Demonstration of a new antibody specificity with polytene chromosomes]. / Ein serologisches Kriterium für Morbus Bechterew. Nachweis einer neuen Antikörperspezifität mit polytänen Chromosomen.
Dtsch Med Wochenschr
; 110(18): 708-13, 1985 May 03.
Article
en De
| MEDLINE
| ID: mdl-3922724
ABSTRACT
A new antibody reacting with an antigen from polytene chromosomes of Drosophila melanogaster has been found in serum of patients with Bechterew's disease. This antigen-antibody system differs from other nuclear antibodies (anti-RNP, anti-Sm, anti-Ha/SS-B) in that it is not detectable by counter-immunoelectrophoresis. The antibody could be detected in 24 out of 62 Morbus Bechterew sera in which the antibody did not strictly correlate with the appearance of HLA-B27 antigen. The new antibody specificity is a specific serological finding in patients with Bechterew's disease and is therefore suitable for use as a diagnostic, and perhaps also as a prognostic test for this type of spondylarthritis till now assumed to be seronegative.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Espondilitis Anquilosante
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Anticuerpos
Tipo de estudio:
Diagnostic_studies
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Prognostic_studies
Límite:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
Idioma:
De
Revista:
Dtsch Med Wochenschr
Año:
1985
Tipo del documento:
Article