[Effect of various adenine derivatives on gastric acid secretion in the isolated rat stomach]. / Efecto de algunos derivados de la adenina sobre la secreción gástrica de ácido en estómago aislado de rata.
Rev Esp Fisiol
; 41(1): 83-7, 1985 Mar.
Article
en Es
| MEDLINE
| ID: mdl-3923579
The adenine derivatives adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP), adenosine 5'-monophosphate (AMP) and adenosine (AD), in concentrations of 10(-3)M and 10(-4)M caused significant and dose-related modifications in the basal acid secretion from isolated whole rat stomach. The first three purine derivatives, ATP, ADP and AMP significantly increased the spontaneous acid secretion. On the other hand, AD caused a significant reduction in the basal acid secretion. When ATP, ADP, AMP and AD were assayed in the presence of the adrenergic and cholinergic blocking agents, ergotamine, 10(-6)M, propranolol, 5 X 10(-7)M and atropine, 10(-6)M, all these purine derivatives, including AD, caused a significant increase in the basal acid secretion.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Nucleótidos de Adenina
/
Adenosina
/
Ácido Gástrico
/
Mucosa Gástrica
Límite:
Animals
Idioma:
Es
Revista:
Rev Esp Fisiol
Año:
1985
Tipo del documento:
Article
Pais de publicación:
España