Reconstruction of 3D Chromosome Structure from Single-Cell Hi-C Data via Recurrence Plots.

Hirata, Yoshito; Sugishita, Hiroki; Gotoh, Yukiko

Hirata, Yoshito; Sugishita, Hiroki; Gotoh, Yukiko.

Afiliación

Hirata Y; Institute of Systems and Information Engineering, University of Tsukuba, Tsukuba, Japan. hirata@cs.tsukuba.ac.jp.
Sugishita H; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo, Tokyo, Japan.
Gotoh Y; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Methods Mol Biol ; 2856: 263-268, 2025.

Article en En | MEDLINE | ID: mdl-39283457

ABSTRACT

ABSTRACT

We describe an approach for reconstructing three-dimensional (3D) structures from single-cell Hi-C data. This approach has been inspired by a method of recurrence plots and visualization tools for nonlinear time series data. Some examples are also presented.

Asunto(s)

Análisis de la Célula Individual; Análisis de la Célula Individual/métodos; Imagenología Tridimensional/métodos; Humanos; Programas Informáticos; Cromosomas/genética; Algoritmos

Palabras clave

Adjacency matrix; Method with mathematical proofs; Recurrence plot; Single diploid cell Hi-C data; Three-dimensional chromosomal reconstruction

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Análisis de la Célula Individual Límite: Humans Idioma: En Revista: Methods Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2025 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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