Full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration.

ABSTRACT

PURPOSE: To describe a case of full thickness macular hole after intravitreal brolucizumab injection in neovascular age-related macular degeneration, which has not been reported to date. CASE DESCRIPTION A 65-year-old male patient received brolucizumab intravitreal injection therapy for neovascular macular degeneration of the right eye. He received multiple intravitreal anti-VEGF injections on a pro re nata regimen and developed a full thickness macular hole. OUTCOME: Surgical treatment was performed with pars plana vitrectomy of the right eye. Full thickness macular hole was successfully treated. CONCLUSION: Although a full thickness macular hole following intravitreal brolucizumab injection is an uncommon complication, it requires caution.