Squamous differentiation in colorectal adenomas. Literature review, histogenesis, and clinical significance.
Dis Colon Rectum
; 29(2): 87-91, 1986 Feb.
Article
en En
| MEDLINE
| ID: mdl-3943426
ABSTRACT
Patterns of stratified squamous epithelium have been recognized recently in colorectal adenomas. Light microscopic and keratin immunohistochemical analysis of four cases in the present report suggested origin from large intestinal reserve cells, with impaired and disorderly maturation in the squamous foci. One case had an invasive adenocarcinoma separately in the same polyp, bringing the reported incidence of malignant transformation in these adenomas to seven of 48 (15 percent). Evidence is presented to support the notion that squamous differentiation may be an inherently neoplastic phenomenon in colorectal adenomas, which may be added to the list of markers for colorectal polyps at higher risk for malignant transformation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias del Recto
/
Adenoma
/
Neoplasias del Colon
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Dis Colon Rectum
Año:
1986
Tipo del documento:
Article