Loss of autoregulation and posttraumatic ischemia following experimental spinal cord trauma.
J Neurosurg
; 50(2): 198-206, 1979 Feb.
Article
en En
| MEDLINE
| ID: mdl-430132
ABSTRACT
Blood flow in the dorsolateral funiculus of the cat thoracic spinal cord was studied after severe experimental cord injury, using a modification of the hydrogen clearance technique. Autoregulation was intact during the initial 60 to 90 minutes after cord injury, but was then lost coincident with the onset of ischemia. The data suggest that the ischemic response to spinal cord injury is mediated both by the loss of autoregulation and by relative vasoconstriction of the resistance vessels. Therapeutic intervention aimed at maintaining perfusion during the early posttraumatic period may prove of value in reversing or limiting some elements of dysfunction due to the secondary injury of ischemia.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Médula Espinal
/
Traumatismos de la Médula Espinal
/
Homeostasis
/
Isquemia
Límite:
Animals
Idioma:
En
Revista:
J Neurosurg
Año:
1979
Tipo del documento:
Article