Conformational analysis of synthetic androgens. IV. 1,2-seco-a-bisnor-5 alpha-androstan-17 beta-ol acetate.
Steroids
; 34(5): 589-95, 1979 Nov.
Article
en En
| MEDLINE
| ID: mdl-516119
ABSTRACT
The crystal and molecular structure of 1,2-seco-A-bisnor-5 alpha-androstan-17beta-ol acetate has been determined to evaluated the conformational importance of the intact steroid nucleus. The resulting tricyclic compound retains nearly the same steric profile for the remainder of the molecule when compared to the structures of dihydrotestosterone derivatives with intact A-rings. This may help to explain why these types of molecules retain a significant level of androgenic activity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Congéneres de la Testosterona
/
Androstanoles
Idioma:
En
Revista:
Steroids
Año:
1979
Tipo del documento:
Article