Protection against bovine leukosis virus infection in sheep with the BL 20 bovine lymphoblastoid cell line.
Vet Immunol Immunopathol
; 3(6): 635-42, 1982 Nov.
Article
en En
| MEDLINE
| ID: mdl-6294966
ABSTRACT
The bovine lymphoblastoid BL 20 cell line derived from a case of sporadic bovine leukosis when inoculated into sheep did not induce an antibody response directed against bovine leukosis virus (BLV) structural proteins. Sheep were inoculated twice with the BL 20 cell line and then challenged with BLV infected lymphocytes. Three out of four sheep challenged four weeks after BL 20 inoculation did not develop BLV antibodies. Of the 12 sheep challenged later, three sheep did not develop BLV antibodies. BLV was isolated from all the seropositive animals and from none of the seronegative animals.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Retroviridae
/
Enfermedades de las Ovejas
/
Vacunas Virales
/
Leucemia
/
Virus de la Leucemia Bovina
Límite:
Animals
Idioma:
En
Revista:
Vet Immunol Immunopathol
Año:
1982
Tipo del documento:
Article