[Structural change in the cell center during fibroblast polarization and movement]. / Izmenenie struktury kletochnogo tsentra pri poliarizatsii i dvizhenii fibroblastov.
Tsitologiia
; 25(8): 883-8, 1983 Aug.
Article
en Ru
| MEDLINE
| ID: mdl-6356531
ABSTRACT
In polarizing and migrating 3T3/Balb mouse fibroblasts, the centrioles are located between the nucleus and the leading edge of the cell. In cells within the monolayer and in migrating cells, the centrioles have a random orientation towards the substrate. In polarized cells, that still remain in the monolayer, one centriole may be perpendicular to the substrate plane in 70% of cases. Upon polarization and migration of fibroblasts, the number of microtubules, which radiate from the centriolar region, increases. These data support a hypothesis that the number of microtubules in the cell centre characterizes the rate of their renovation in the cytoplasm. It is concluded that the cell centre is strongly involved in polarization and migration of fibroblasts.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Organoides
/
Centriolos
/
Fibroblastos
Límite:
Animals
Idioma:
Ru
Revista:
Tsitologiia
Año:
1983
Tipo del documento:
Article