The distribution of dermal tumorigens in coal liquids: relationship of tumorigenicity and microbial mutagenicity.
J Appl Toxicol
; 4(3): 117-23, 1984 Jun.
Article
en En
| MEDLINE
| ID: mdl-6379026
ABSTRACT
Polycyclic aromatic hydrocarbons and/or their pyrolle derivatives were found to be the primary contributors to the skin tumorigenicity of the neutral fractions of two coal oils. Mutagenicity of the neutral fraction in Salmonella test strains was found to be due primarily to polycyclic aromatics containing polar substituents. Thus, the chemical classes responsible for skin tumorigenicity differ from those responsible for mutagenicity.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Policíclicos
/
Neoplasias Cutáneas
/
Aceites Combustibles
/
Petróleo
/
Carbón Mineral
/
Mutágenos
Límite:
Animals
Idioma:
En
Revista:
J Appl Toxicol
Año:
1984
Tipo del documento:
Article