Experimental infection of chimpanzees with the HBsAg-associated delta (delta) agent: an ultrastructural study.
J Med Virol
; 13(1): 63-72, 1984.
Article
en En
| MEDLINE
| ID: mdl-6420512
ABSTRACT
Characteristic cytoplasmic membranous structures and intranuclear aggregates of particles similar to those reported in non-A, non-B hepatitis were observed by electron microscopy in the liver biopsies of chimpanzees inoculated with human serum, infectious for the delta agent. The ultrastructural changes were maximal during the intrahepatic production of the delta antigen, but were detected also independently of delta-Ag expression. The ultrastructural analogies provide further evidence that delta has properties distinct from HBV.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hepatitis
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Med Virol
Año:
1984
Tipo del documento:
Article
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA