Lithium-induced increases in red blood cell choline and memory performance in Alzheimer-type dementia.
Biol Psychiatry
; 19(2): 157-64, 1984 Feb.
Article
en En
| MEDLINE
| ID: mdl-6424733
ABSTRACT
To investigate the relationship between RBC choline and memory in Alzheimer-type senile dementia (SDAT), lithium carbonate was administered to 14 SDAT patients in doses of 400-600 mg/day for 5 weeks. A battery of memory tests was administered at baseline and at weekly intervals. Five patients with serum concentrations below 0.6 meq/liter developed neurotoxicity and were dropped from further analysis. For the remaining patients, Li+ with mean serum concentrations up to 0.6 meq/liter did not alter memory scores significantly. The dramatic increases in RBC choline during the study, however, suggest that RBC choline is not correlated with memory functioning in SDAT.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Colina
/
Eritrocitos
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Enfermedad de Alzheimer
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Litio
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Memoria
Límite:
Aged
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Humans
/
Middle aged
Idioma:
En
Revista:
Biol Psychiatry
Año:
1984
Tipo del documento:
Article
Pais de publicación:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
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UNITED STATES
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UNITED STATES OF AMERICA
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US
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USA