Gamma-vinyl-GABA: a single-blind trial in patients with epilepsy.
Acta Neurol Scand
; 68(1): 34-9, 1983 Jul.
Article
en En
| MEDLINE
| ID: mdl-6613525
ABSTRACT
The anti-epileptic effect of gamma-vinyl-GABA (GVG) was studied using a placebo-controlled, single-blind design in 15 patients with therapy-resistant epilepsy, the majority experiencing complex partial seizures. GVG was added to concomitant treatment, which was kept at constant serum levels. Following administration of 1 g, 2 g and 3 g per day, significant reductions in seizure frequency were observed. A poor correlation was found between GVG serum levels and clinical effect. Only mild and transient side-effects were observed.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Epilepsia
/
Aminocaproatos
/
Anticonvulsivantes
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Acta Neurol Scand
Año:
1983
Tipo del documento:
Article