The treatment of experimental allergic neuritis by plasma exchange.
J Neurol Sci
; 61(2): 149-60, 1983 Oct.
Article
en En
| MEDLINE
| ID: mdl-6644324
ABSTRACT
Experimental allergic neuritis (EAN) is a demyelinating disease of the peripheral nervous system that can be induced in laboratory animals. This disorder has been considered to show many similarities to acute inflammatory polyneuropathy (Guillain-Barré syndrome, GBS). Reports that plasma exchange may benefit patients with GBS prompted the investigation of the effect of plasma exchange in EAN. A controlled study was performed on New Zealand White rabbits. Sixteen animals were allocated to control or treatment groups at the onset of the disease. Clinical assessment on days 7 and 14 showed that treated animals were less severely affected neurologically (P = 0.05, day 7; P less than 0.001 day 14), with a commensurate reduction in the severity of the histological lesions in peripheral nerves.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Intercambio Plasmático
/
Neuritis Autoinmune Experimental
Límite:
Animals
Idioma:
En
Revista:
J Neurol Sci
Año:
1983
Tipo del documento:
Article