In-vitro antigonococcal activity of rosoxacin (WIN 35213).
Br J Vener Dis
; 57(1): 33-5, 1981 Feb.
Article
en En
| MEDLINE
| ID: mdl-6781706
The in-vitro activity of rosoxacin against 173 isolates of Neisseria gonorrhoeae, including 17 beta-lactamase-producers, was tested by an agar dilution method. Of the isolates, 167 (including 16 of the beta-lactamase-producers) were inhibited by 0 . 06 mg/l of rosoxacin. The remaining six isolates, one of which produced beta-lactamase and the others were moderately resistant to penicillin, were inhibited by 0 . 12-0 25 mg/l of the compound. There was little correlation between the minimum inhibitory concentrations (MICs) of rosoxacin and penicillin, except for isolates with MICs of penicillin of 0 . 06-1 mg/l, for which correlation was good.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quinolinas
/
Quinolonas
/
4-Quinolonas
/
Antibacterianos
/
Neisseria gonorrhoeae
Idioma:
En
Revista:
Br J Vener Dis
Año:
1981
Tipo del documento:
Article
Pais de publicación:
Reino Unido