Angiotensin synthesis in the brain and increased turnover in hypertensive rats.
Science
; 221(4613): 869-71, 1983 Aug 26.
Article
en En
| MEDLINE
| ID: mdl-6879184
ABSTRACT
The missing link in the evidence for an active endogenous renin angiotensin system in the brain has been the demonstration of local angiotensin synthesis in the central nervous system in vivo. In this report the extraction and characterization of angiotensin I and angiotensin II from the brain of rats is described. The accumulation of angiotensin I was enhanced in hypertensive rats when the conversion to angiotensin II was blocked in vivo by the converting enzyme inhibitor captopril.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Encéfalo
/
Angiotensinas
/
Hipertensión
Límite:
Animals
Idioma:
En
Revista:
Science
Año:
1983
Tipo del documento:
Article