Inversion of D-tryptophan to L-tryptophan and excretory patterns in the rat and chick.
J Nutr
; 110(4): 641-8, 1980 Apr.
Article
en En
| MEDLINE
| ID: mdl-7365535
ABSTRACT
The behavior of D-tryptophan in the blood plasma and the pattern of tryptophan excretion in the urine were studied in the rat and the chick. When D-tryptophan was administered orally to rats and chicks, both showed D-tryptophan in the plasma. Conversion of D-tryptophan to the L-isomer in the rat was found by an examination of plasma from the posterior vena cava and the portal vein, following stomach intubation of 100 micromoles D-tryptophan/100 g of body weight. The peak in the increase of L-tryptophan was approximately 150 nmoles/ml plasma when measured at 30 minutes after administration and the peak was 200 nmoles when measured 2 hours after administration. No conversion of D-tryptophan to the L-isomer was found in chicks. Under similar conditions, D-tryptophan was measured in the urine of rats and chicks. In rats the D-tryptophan excreted was at most 1% of the amount administered; while in chicks most of the D-tryptophan was excreted.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Ratas
/
Triptófano
/
Pollos
Límite:
Animals
Idioma:
En
Revista:
J Nutr
Año:
1980
Tipo del documento:
Article