Strange-male-induced pregnancy disruption in mice: reduction of vulnerability by 17 beta-estradiol antibodies.
Physiol Behav
; 58(2): 401-4, 1995 Aug.
Article
en En
| MEDLINE
| ID: mdl-7568446
ABSTRACT
It is well-established that novel males can disrupt early pregnancy in house mice. Inseminated female C57BL mice were either left undisturbed or each exposed indirectly to a novel HS male through a wire-mesh grid during days 1-6 of pregnancy. Varied dosages of antibodies to 17 beta-estradiol were administered to females exposed to males. Vehicle-treated females exposed to novel males showed fewer litters than did nonexposed controls. Male-exposed females given 1 ml daily of the antibody showed rates of pregnancy comparable to those observed in controls. These data suggest that estrogen levels might play a role in strange-male-induced pregnancy disruptions, converging with evidence implicating estrogens in stress-induced pregnancy blocks.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Preñez
/
Resultado del Embarazo
/
Estradiol
/
Anticuerpos
Límite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Physiol Behav
Año:
1995
Tipo del documento:
Article
País de afiliación:
Canadá