A Saccharomyces cerevisiae gene essential for viability has been conserved in evolution.
Gene
; 160(1): 135-6, 1995 Jul 04.
Article
en En
| MEDLINE
| ID: mdl-7628709
ABSTRACT
To identify the gene coding for the endonuclease which processes the 3' end of mitochondrial (mt) tRNA transcripts in Saccharomyces cerevisiae, nuclear mutations able to complement a mt mutant (Ts932) defective for this process were isolated and analyzed. One of these mutants exhibited a growth defect both on respiratory and fermentable media. Complementation of this phenotype with a S. cerevisiae centrometric wild-type genomic library has allowed us to identify a new essential S. cerevisiae gene strongly conserved in various eukaryotic organisms.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saccharomyces cerevisiae
/
ARN de Transferencia de Aspártico
/
Secuencia Conservada
/
Evolución Biológica
/
Genes Fúngicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Gene
Año:
1995
Tipo del documento:
Article
País de afiliación:
Italia