Long-term therapy of essential tremor with flunarizine.
Eur Neurol
; 35(4): 217-9, 1995.
Article
en En
| MEDLINE
| ID: mdl-7671982
ABSTRACT
We investigated the effect of long-term treatment of essential tremor (ET) with flunarizine (Fz) (10 mg/day) in 17 subjects who had a favorable response to 1 month of treatment. Side effects (dystonia, parkinsonism, weight gain and depression) occurred in 29.4% (5/17) of patients, leading to drug discontinuation. Fz was still effective at the end of 30 months of treatment in 41% (7/17) of patients. Loss of efficacy was observed in 29.4% (5/17) of patients. It is concluded that Fz is an alternative for long-term treatment of patients with ET; however, loss of efficacy and side effects are common.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Temblor
/
Flunarizina
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Eur Neurol
Año:
1995
Tipo del documento:
Article
País de afiliación:
Arabia Saudita