[Diabetes, obesity, hypertension and the autonomic nervous system]. / Diabete, obesità, ipertensione e sistema nervoso vegetativo.
Minerva Endocrinol
; 19(3): 105-11, 1994 Sep.
Article
en It
| MEDLINE
| ID: mdl-7799891
ABSTRACT
Functional changes of the autonomic nervous system may represent a common pathophysiologic factor in the association between non insulin-dependent diabetes, obesity, and essential hypertension. In all these conditions a number of sympathetic and/or parasympathetic dysfunctions consistent with autonomic neuropathy or simply with functional adaptations to haemodynamic changes have been reported. Autonomic neuropathy is a well known diabetic complication which is responsible for some clinical aspects of different severity. Subtle sympathetic and parasympathetic abnormalities possibly affecting thermogenesis have been shown in obese people. An increased sympathetic activity has been proposed as one of the pathogenetic mechanisms of essential hypertension. Finally, the association between diabetes, obesity, hypertension and sympathetic overactivity could be explained by a common trans-membrane ionic disturbance with an increase of intracellular calcium and a decrease of both intracellular magnesium and pH.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sistema Nervioso Autónomo
/
Diabetes Mellitus Tipo 2
/
Hipertensión
/
Obesidad
Límite:
Humans
Idioma:
It
Revista:
Minerva Endocrinol
Año:
1994
Tipo del documento:
Article