A gene transfer method for the study of chimerism derived from donor bone marrow in organ transplant recipients.
Transplant Proc
; 27(1): 182-3, 1995 Feb.
Article
en En
| MEDLINE
| ID: mdl-7878965
ABSTRACT
Transduction of DBMC with the neo gene did not negatively affect the viability of DBMC or the graft-prolonging effect of DBMC infusion and provided a sensitive method to monitor DBMC-derived chimerism at a microchimeric level for at least 6 months by molecular and immunohistochemical techniques. Selection of neo-transduced DBMC with G418 prior to infusion will enable more uniform neo expression and will provide novel opportunities to further investigate chimerism in primates.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quimera
/
Trasplante de Médula Ósea
/
Trasplante de Riñón
/
Técnicas de Transferencia de Gen
/
Trasplante de Células
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Transplant Proc
Año:
1995
Tipo del documento:
Article