Glutamine and glutamate in ascitic fluid of dogs.
Eur J Clin Chem Clin Biochem
; 31(2): 103-6, 1993 Feb.
Article
en En
| MEDLINE
| ID: mdl-8096769
ABSTRACT
The amino acid pattern in the ascites of 79 dogs was examined. The concentration of glutamine in neoplastic ascites is significantly lower than in cardial effusions. In contrast, glutamate is significantly higher in neoplastic ascites than in cardial ascites. Using an arbitrary discrimination value of 0.28 for the glutamate/glutamine ratio, purulent or cardial ascites are easily differentiated, with a sensitivity of 100% and a specificity of 94%. The differentiation is very distinct, with no overlap between the group of patients with liver cirrhosis on the one hand and the groups of patients with purulent peritonitis, heart failure, or malignant ascites on the other hand. There was no diagnostically unsable correlation between the concentrations of the other 20 amino acids and the underlying causes of ascites formation.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Líquido Ascítico
/
Glutamatos
/
Glutamina
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Eur J Clin Chem Clin Biochem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA CLINICA
Año:
1993
Tipo del documento:
Article