Desensitization to sulphasalazine in patients with arthritis.

ABSTRACT

Desensitization to sulphasalazine was successful in 16 of 21 (76%) arthritic patients who previously had skin rash from sulphasalazine (success rate 8 of 13, or 62%) or sulphonamide (success rate 8 out of 8 patients). Desensitization to sulphasalazine is a simple outpatient procedure which allows many subjects who develop a skin rash to sulphonamide or sulphasalazine to start or continue sulphasalazine treatment.