Ambulatory blood pressure measurement in assessing the antihypertensive effect of benazepril plus hydrochlorothiazide in a fixed combination.
Clin Ther
; 15(4): 650-6, 1993.
Article
en En
| MEDLINE
| ID: mdl-8221814
Ambulatory 24-hour blood pressure monitoring was used to assess the antihypertensive efficacy of the angiotensin-converting enzyme (ACE) inhibitor benazepril in combination with the diuretic hydrochlorothiazide (HCTZ) in 17 mildly to moderately hypertensive patients. Compared with placebo, benazepril 10 mg + HCTZ 12.5 mg induced a statistically and clinically significant reduction in the mean, systolic, and diastolic blood pressures. Cumulative percentages of diastolic blood pressure readings < 90 mmHg were also greater with the combination treatment than with placebo. No patient discontinued the treatment because of adverse effects.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Benzazepinas
/
Presión Sanguínea
/
Hidroclorotiazida
/
Hipertensión
Tipo de estudio:
Clinical_trials
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Clin Ther
Año:
1993
Tipo del documento:
Article
País de afiliación:
Italia
Pais de publicación:
Estados Unidos