The preservation of renal function by isovolemic hemodilution during aortic operations.
J Vasc Surg
; 18(5): 858-66, 1993 Nov.
Article
en En
| MEDLINE
| ID: mdl-8230574
ABSTRACT
PURPOSE:
In an investigation of the effects of isovolemic hemodilution, 39 consecutive patients undergoing elective infrarenal aortic operation had detailed measurements of renal function, renal artery blood flow, and cardiac hemodynamics.METHODS:
The patients were randomly allocated to receive acute preoperative isovolemic hemodilution to a hematocrit of 28%, with 20 patients receiving hemodilution and 19 being control subjects.RESULTS:
Twelve (63%) of the control group had renal impairment, compared with only four (20% in the group receiving hemodilution (p < 0.01). Hemodilution also prevented the fall in cardiac output induced by cross-clamping (p < 0.01) and significantly reduced the need for transfusion of donor blood (p < 0.01).CONCLUSIONS:
Acute isovolemic hemodilution is clearly a useful adjunct in the management of patients undergoing elective aortic operation.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aorta Abdominal
/
Hemodilución
/
Riñón
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Observational_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Vasc Surg
Asunto de la revista:
ANGIOLOGIA
Año:
1993
Tipo del documento:
Article
País de afiliación:
Reino Unido