Modulation of the respiratory burst in human neutrophils by isoproterenol and dibutyryl cyclic AMP.
J Neuroimmunol
; 43(1-2): 59-68, 1993 Mar.
Article
en En
| MEDLINE
| ID: mdl-8384637
ABSTRACT
The effects of a beta-adrenergic agonist and a cyclic AMP analogue on activation, activity, and termination of FMLP-stimulated superoxide anion production were investigated. Incubation with isoproterenol resulted in a 50% reduction in the maximal rate of superoxide production and a 3-4-fold increase in the rate of termination of superoxide production. Exposure to 1 mM dibutyryl cyclic AMP resulted in a 40% decrease in the maximal rate and a 3-fold increase in the rate of termination of FMLP-induced superoxide production. Neither agent had a significant effect on the lag time prior to superoxide anion generation.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Estallido Respiratorio
/
Bucladesina
/
Isoproterenol
/
Neutrófilos
Límite:
Humans
Idioma:
En
Revista:
J Neuroimmunol
Año:
1993
Tipo del documento:
Article