Molecular alterations in a patient with Turcot's syndrome.
Br J Cancer
; 68(3): 519-23, 1993 Sep.
Article
en En
| MEDLINE
| ID: mdl-8394730
ABSTRACT
Cells of a patient with Turcot's syndrome and of her parents were evaluated for the presence of molecular alterations in the p53 and the Ki-ras gene. Deletions on chromosome 17p, overexpression and point mutations of the p53 gene as well as mutations of the Ki-ras gene were detected in primary and metastatic tumour but not in the germline of the patient nor in her parents.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Encefálicas
/
Genes p53
/
Genes ras
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Poliposis Adenomatosa del Colon
Límite:
Adolescent
/
Humans
Idioma:
En
Revista:
Br J Cancer
Año:
1993
Tipo del documento:
Article