Effects of irradiation on surface carbohydrates of larvae of Schistosoma mansoni.
Parasitology
; 106 ( Pt 2): 117-25, 1993 Feb.
Article
en En
| MEDLINE
| ID: mdl-8446469
ABSTRACT
Ultra-violet irradiated larvae of Schistosoma mansoni stimulate high levels of resistance to challenge infection in experimental animals. In the experiments presented here, the binding patterns of antisera specific for the cercarial glycocalyx, and of various lectins, demonstrate that u.v. irradiation causes a pronounced modification of the carbohydrate antigens expressed at the surface of cercariae and newly transformed schistosomula. These alterations were dependent on the irradiation dose, and on the batch of cercariae used in each experiment. Our results strongly suggest that the changes in carbohydrate antigens consequent upon u.v. irradiation may be important in generating the enhanced immunogenicity of irradiated cercariae.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polisacáridos
/
Schistosoma mansoni
/
Rayos Ultravioleta
/
Carbohidratos
/
Glicoproteínas
/
Antígenos Helmínticos
Límite:
Animals
Idioma:
En
Revista:
Parasitology
Año:
1993
Tipo del documento:
Article
País de afiliación:
Reino Unido