Synergy of levofloxacin (L-ofloxacin) and oxacillin against quinolone-resistant Staphylococcus aureus, measured by the time-kill method.
Antimicrob Agents Chemother
; 37(2): 339-41, 1993 Feb.
Article
en En
| MEDLINE
| ID: mdl-8452367
ABSTRACT
The synergistic activity of levofloxacin and oxacillin against levofloxacin-resistant isolates of methicillin-resistant Staphylococcus aureus was tested by the time-kill method. The combination of levofloxacin at 1/4 the MIC for the isolate plus oxacillin at 8 micrograms/ml (< 1/4 the MIC) was synergistic against seven of nine isolates at 8 h, although no significant synergy was demonstrated at 24 h. This combination may prove to be effective against multidrug-resistant methicillin-resistant S. aureus, and further studies are warranted.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oxacilina
/
Staphylococcus aureus
/
Ofloxacino
/
Levofloxacino
/
Antiinfecciosos
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
1993
Tipo del documento:
Article