[Duplex sonographic studies on the pathogenesis of splenic hemodynamics in liver cirrhosis]. / Duplexsonographische Untersuchungen zur Pathogenese der lienalen Hämodynamik bei Leberzirrhose.
Dtsch Med Wochenschr
; 121(3): 52-6, 1996 Jan 19.
Article
en De
| MEDLINE
| ID: mdl-8565810
ABSTRACT
AIM OF STUDY The haemodynamic role of the spleen in portal hypertension remains unclear. Duplex sonography was undertaken prospectively to discover the relationship of splenomegaly and splenic vein flow to type and severity of liver cirrhosis and portal vein flow, as well as to the degree of oesophageal varices. PATIENTS AND METHODS:
89 patients (54 men, 35 women; mean age 52 [26-81] years), diagnosed in the second half of 1993 as having liver cirrhosis were consecutively included in the study. In 40 patients the cirrhosis was in stage A (according to Child-Pugh classification), in 31 in stage B and in 18 in stage C.RESULTS:
Portal vein flow fell significantly with increasing degree of cirrhosis (stage A 8.29 cm/s; stage B 7.03 cm/s; stage C 5.26 cm/s; P < 0.05). Splenic vein flow differed significantly only between stages B and C (stage A 9.22 cm/s; stage B 9.46 cm/s; stage C 7.87 cm/s; B vs C, P < 0.05). There was no correlation between portal vein flow, splenic vein flow, degree of splenomegaly and extent of oesophageal varices.CONCLUSION:
The results may be explained by the presence of collateral circulations and by the differing pathophysiological part played by the spleen in liver cirrhosis of different aetiologies.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bazo
/
Cirrosis Hepática
Tipo de estudio:
Etiology_studies
/
Observational_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
De
Revista:
Dtsch Med Wochenschr
Año:
1996
Tipo del documento:
Article