Localization of the CD15-epitope in the inner ear of the developing mouse.
Cell Tissue Res
; 283(3): 395-401, 1996 Mar.
Article
en En
| MEDLINE
| ID: mdl-8593669
ABSTRACT
The expression of the 3-fucosyl-N-acetyl-lactosamine (CD15) epitope during the embryonic development of the mouse inner ear has been immunohistochemically studied on paraffin sections from day 8.5 to day 19 of gestation. Consecutive steps of morphological development are accompanied by up- and down-regulation of CD15 expression and changing cell patterns. Expression levels are reduced once structural maturation has been accomplished. Since CD15 has been described as a determinant that is expressed during critical developmental steps, it is speculated that the changes in the epitope expression in the inner ear reflect relevant stages of differentiation. This system may thus serve as a model for understanding inner ear development.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antígeno Lewis X
/
Oído Interno
/
Ratones Endogámicos
/
Epítopos
Límite:
Animals
Idioma:
En
Revista:
Cell Tissue Res
Año:
1996
Tipo del documento:
Article
País de afiliación:
Alemania