Determination of PCB metabolites in Canadian human milk.
Chemosphere
; 33(3): 559-65, 1996 Aug.
Article
en En
| MEDLINE
| ID: mdl-8680832
ABSTRACT
Chlorinated biphenyl methylsulfones and biphenylols were determined in samples of human milk from Canadian donors. Fifty samples containing an average of 10.8 ng g-1 (w/w) of total PCBs were found to contain an average of 68 pg g-1 of chlorinated biphenyl methylsulfone. The major congeners were 3-methylsulfonyl-2,2',4',5,5',-pentachlorobiphenyl, 4-methylsulfonyl-2,2',3',4',5,-pentachlorobiphenyl and 4-methylsulfonyl-2,2',3',5,5',6'-hexachlorobiphenyl. Twelve of these samples were analyzed for five chlorinated biphenylols and the 4-methoxy-2,2',3,4',5,5',6-heptachlorobiphenylol congener was detected in all at an average concentration of 1.9 pg g-1. The chlorinated biphenylols appear to be minor residual metabolites in human milk from the general population. The fifty samples with an average of 8.4 ng g-1 of p,p'-DDE also contained an average of 16.5 pg g-1 of the corresponding methylsulfone. Both the total PCB methylsulfone and p,p' DDE methylsulfone were correlated with total PCB and p,p' DDE contents, respectively.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Residuos de Plaguicidas
/
Bifenilos Policlorados
/
Leche Humana
Límite:
Female
/
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Chemosphere
Año:
1996
Tipo del documento:
Article
País de afiliación:
Canadá